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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | Facultad de Ciencias Exactas y Naturales de la UBA | - |
| dc.contributor | Somoza, Gustavo Manuel | - |
| dc.contributor | Stefano, Andrea Virginia | - |
| dc.creator | Stefano, Andrea Virginia | - |
| dc.date.accessioned | 2018-05-04T22:05:30Z | - |
| dc.date.accessioned | 2018-05-28T16:35:26Z | - |
| dc.date.available | 2018-05-04T22:05:30Z | - |
| dc.date.available | 2018-05-28T16:35:26Z | - |
| dc.date.issued | 1999 | - |
| dc.identifier.uri | http://10.0.0.11:8080/jspui/handle/bnmm/73545 | - |
| dc.description | Gonadotropin-releasing hormone (GnRH) variants were characterized by gradient reverse phase high performance liquid chromatography (RP-HPLC) and radioimmunoassays with different antisera in brain and pituitary extracts of pejerrey, Odontesthes bonariensis (Atheriniformes). The results showed that three forms of GnRH are expressed in brain tisuue: two of them are chromatographic and immunologically similar to cGnRH-II (chicken) and sGnRH (salmon) while the third GnRH appeared to be different from the eleven known forms of the vertebrate hormone. This novel form is the only variant present in pituitary gland extracts. The distribution of GnRH neurons and fibers in the brain was demonstrated with immunocytochemical methods using specific antisera. The results indicate that ir-GnRH perikaria were observed in three different nucleus: nucleus olfactoretinalis, nucleus preopticus periventricularis and in the midbrain tegmentum. Immunoreactive GnRH (ir-GnRH) fibers reached the three areas of the adenohypophisis: rostral pars distalis, proximal pars distalis and pars intermedia. A close association between ir-GnRH fibers with growth hormone (GH) and prolactin (PRL) cells in the pituitary gland was also demonstrate. Furthermore, colocalization of GnRH receptors with somatotropin and prolactin expressing cells in pituitary primary cell culture was also shown. | - |
| dc.description | Fil:Stefano, Andrea Virginia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. | - |
| dc.format | application/pdf | - |
| dc.language | spa | - |
| dc.publisher | Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | http://creativecommons.org/licenses/by/2.5/ar | - |
| dc.source.uri | http://digital.bl.fcen.uba.ar/gsdl-282/cgi-bin/library.cgi?a=d&c=tesis&d=Tesis_3134_Stefano | - |
| dc.title | Caracterización bioquímica de las variantes de GnRH (gonadotropin-releasing hormone) presentes en cerebro e hipófisis de pejerrey, Odontesthes bonariensis : Localización neuroanatómica y relación con distintas hormonas hipofisisarias | - |
| dc.title | Characterization of GnRH (gonadotropin releasing-hormone) variants in the brain and pituitary gland of pejerrey, Odontesthes bonariensis : Neuroanatomical localization and relation with different pituitary hormones | - |
| dc.type | info:eu-repo/semantics/doctoralThesis | - |
| dc.type | info:ar-repo/semantics/tesis doctoral | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| Aparece en las colecciones: | FCEN - Facultad de Ciencias Exactas y Naturales. UBA | |
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