Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | INTA | - |
| dc.contributor | Del Medico Zajac, Maria Paula | - |
| dc.contributor | Zanetti, Flavia Adriana | - |
| dc.contributor | Esusy, María Soledad | - |
| dc.contributor | Federico, Carlos Rodolfo | - |
| dc.contributor | Zabal, Osvaldo Alfredo | - |
| dc.contributor | Valera, Alejandro Rafael | - |
| dc.contributor | Calamante, Gabriela | - |
| dc.creator | Del Medico Zajac, Maria Paula | - |
| dc.creator | Zanetti, Flavia Adriana | - |
| dc.creator | Esusy, María Soledad | - |
| dc.creator | Federico, Carlos Rodolfo | - |
| dc.creator | Zabal, Osvaldo Alfredo | - |
| dc.creator | Valera, Alejandro Rafael | - |
| dc.creator | Calamante, Gabriela | - |
| dc.date | 2017-08-14T12:49:13Z | - |
| dc.date | 2017-08-14T12:49:13Z | - |
| dc.date | 2017 | - |
| dc.date.accessioned | 2019-04-29T16:26:24Z | - |
| dc.date.available | 2019-04-29T16:26:24Z | - |
| dc.date.issued | 2017-08-14T12:49:13Z | - |
| dc.date.issued | 2017-08-14T12:49:13Z | - |
| dc.date.issued | 2017 | - |
| dc.identifier | 1557-8976 (Online) | - |
| dc.identifier | 0882-8245 (Print) | - |
| dc.identifier | https://doi.org/10.1089/vim.2016.0090 | - |
| dc.identifier | http://hdl.handle.net/20.500.12123/960 | - |
| dc.identifier | http://online.liebertpub.com/doi/10.1089/vim.2016.0090 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/313268 | - |
| dc.description | In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D (MVA-gDs) without addition of adjuvant in two animal models. First, we demonstrated the capability of MVA-gDs of inducing both local and systemic anti-gD humoral immune response after intranasal immunization of mice. Then, we confirmed that two doses of MVA-gDs administered intranasally to rabbits induced systemic anti-gD antibodies and conferred protection against BoHV-1 challenge. Our results show the potential of using MVA as a vector for the rational design of veterinary vaccines capable of inducing specific and protective immune responses both at local and systemic level. | - |
| dc.description | Inst. de Biotecnología | - |
| dc.description | Fil: Del Medico Zajac, Maria Paula. INTA. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Zanetti, Flavia Adriana. INTA. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Esusy, María Soledad. INTA. Instituto de Biotecnología; Argentina | - |
| dc.description | Fil: Federico, Carlos Rodolfo. INTA. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Zabal, Osvaldo Alfredo. INTA. Instituto de Virología; Argentina | - |
| dc.description | Fil: Valera, Alejandro Rafael. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Cátedra de Virología; Argentina | - |
| dc.description | Fil: Calamante, Gabriela. INTA. Instituto de Biotecnología; Argentina | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.source | Viral Immunology 30 (1) : 70-76 | - |
| dc.source | reponame:INTA Digital (INTA) | - |
| dc.source | instname:Instituto Nacional de Tecnología Agropecuaria | - |
| dc.source | instacron:INTA | - |
| dc.source.uri | 1557-8976 (Online) | - |
| dc.source.uri | 0882-8245 (Print) | - |
| dc.source.uri | https://doi.org/10.1089/vim.2016.0090 | - |
| dc.source.uri | http://hdl.handle.net/20.500.12123/960 | - |
| dc.source.uri | http://online.liebertpub.com/doi/10.1089/vim.2016.0090 | - |
| dc.source.uri | https://doi.org/10.1089/vim.2016.0090 | - |
| dc.source.uri | http://hdl.handle.net/20.500.12123/960 | - |
| dc.source.uri | http://online.liebertpub.com/doi/10.1089/vim.2016.0090 | - |
| dc.subject | Enfermedades de los Animales | - |
| dc.subject | Respuesta inmunológica | - |
| dc.subject | Ratón | - |
| dc.subject | Herpes Virus Bovino | - |
| dc.subject | Glicoproteínas | - |
| dc.subject | Immune response | - |
| dc.subject | Animal Diseases | - |
| dc.subject | Mice | - |
| dc.subject | Bovine herpesvirus | - |
| dc.subject | Glycoproteins | - |
| dc.title | Induction of both local immune response in mice and protection in a rabbit model by intranasal immunization with modified vaccinia ankara virus expressing a secreted form of bovine herpesvirus 1 glycoprotein D | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/acceptedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | INTA | |
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