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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | Comisión de Investigaciones Científicas | - |
| dc.contributor | Machicote, Roberta G. | - |
| dc.contributor | Castillo, Marcela A. | - |
| dc.contributor | Pacheco, María Emilia | - |
| dc.contributor | Bruzzone, Liliana | - |
| dc.creator | Machicote, Roberta G. | - |
| dc.creator | Castillo, Marcela A. | - |
| dc.creator | Pacheco, María Emilia | - |
| dc.creator | Bruzzone, Liliana | - |
| dc.date | 2018 | - |
| dc.date.accessioned | 2019-04-29T16:05:15Z | - |
| dc.date.available | 2019-04-29T16:05:15Z | - |
| dc.date.issued | 2018 | - |
| dc.identifier | http://digital.cic.gba.gob.ar/handle/11746/7496 | - |
| dc.identifier | Recurso online | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/308856 | - |
| dc.description | A flow-through optosensing system for oxazepam recognition with fluorescence detection was performed by means of a molecular imprinted polymer based on its acid hydrolysis product, 2-amino-5-chlorobenzophenone. )e synthesis was conducted via a noncovalent imprinting methodology, using methacrylic acid as a functional monomer and ethylene glycol dimethacrylate as a cross-linking agent. Hydrolysis (types and concentration of acids), polymer retention capacity, binding properties, and elution (selectivity and reversibility) conditions were optimized. )e selected molecular imprinted polymer had a molar ratio composition of 1 : 6 : 45 (template : functional monomer : cross-linker). )e proposed method was applied to the determination of oxazepam in a pharmaceutical formulation. External standard calibration, standard additions calibration, and Youden’s calibration were carried out in order to evaluate constant and proportional errors due to the matrix. )e developed metabolite-based recognition system for benzodiazepines is an innovative procedure that could be followed in routine and quality control assays. | - |
| dc.format | application/pdf | - |
| dc.format | 7 p. | - |
| dc.language | eng | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | Attribution 4.0 International (BY 4.0) | - |
| dc.source | reponame:CIC Digital (CICBA) | - |
| dc.source | instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires | - |
| dc.source | instacron:CICBA | - |
| dc.source.uri | http://digital.cic.gba.gob.ar/handle/11746/7496 | - |
| dc.source.uri | Recurso online | - |
| dc.subject | Ciencias Químicas | - |
| dc.title | A Molecular Imprinted Polymer as a Flow-Through Optical Sensor for Oxazepam | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | Comisión de Investigaciones Científicas de la Prov. de Buenos Aires | |
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