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dc.creatorPalomar, Martín Manuel-
dc.creatorMaldonado Galdeano, María Carolina-
dc.creatorPerdigón, Gabriela del Valle-
dc.date2015-10-26T17:49:41Z-
dc.date2015-10-26T17:49:41Z-
dc.date2014-01-
dc.date2016-03-30 10:35:44.97925-03-
dc.date.accessioned2019-04-29T15:57:17Z-
dc.date.available2019-04-29T15:57:17Z-
dc.identifierPalomar, Martín Manuel; Maldonado Galdeano, María Carolina; Perdigón, Gabriela del Valle; Influence of a lactobacillus probiotic strain on the intestinal ecosystem in a stress model in mouse; Academic Press; Brain Behavior And Immunity; 35; 1-2014; 77-85-
dc.identifier0889-1591-
dc.identifierhttp://hdl.handle.net/11336/2564-
dc.identifier1090-2139-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/306132-
dc.descriptionDaily exposure to stressful situations affects the health of humans and animals. It has been shown that psychological stress affects the immune system and can exacerbate diseases. Probiotics can act as biological immunomodulators in healthy people, increasing both intestinal and systemic immune responses. The use of probiotics in stress situations may aid in reinforcing the immune system. The aim of this study was to evaluate the effect of a probiotic bacterium on the gut immune system of mice that were exposed to an experimental model of stress induced by food and mobility restriction. The current study focused on immune cells associated with the lamina propria of the intestine, including CD4+ and CD8+ T lymphocytes, CD11b+ macrophages, CD11c+ dendritic cells, and IgA+ B lymphocytes, as well as the concentrations of secretory IgA (S-IgA) and cytokine interferon gamma (INF-c in intestinal fluid. We also evaluated the probiotic?s influence on the gut microbiota. Probiotic administration increased IgA producing cells, CD4+ cells in the lamina propria of the small intestine, and S-IgA in the lumen; it also reduced the levels of IFN-c that had increased during stress and improved the intestinal microbiota as measured by an increase in the lactobacilli population. The results obtained from administration of the probiotic to stressed mice suggest that the use of food containing these microorganisms may work as a palliative to reinforce the immune system.-
dc.descriptionFil: Palomar, Martín Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia para Lactobacilos (i); Argentina;-
dc.descriptionFil: Maldonado Galdeano, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia para Lactobacilos (i); Argentina; Universidad Nacional de Tucuman. Facultad de Bioquimica, Quimica y Farmacia. Instituto de Microbiologia; Argentina;-
dc.descriptionFil: Perdigón, Gabriela del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia para Lactobacilos (i); Argentina; Universidad Nacional de Tucuman. Facultad de Bioquimica, Quimica y Farmacia. Instituto de Microbiologia; Argentina;-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherAcademic Press-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.bbi.2013.08.015-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0889159113004492-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.bbi.2013.08.015-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/journal/08891591-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectSTRESS-
dc.subjectINTESTINAL ECOSYSTEM-
dc.subjectINTESTINAL MICROBIOTA-
dc.subjectPROBIOTICS-
dc.subjectIG A PRODUCING CELLS-
dc.subjectInmunología-
dc.subjectMedicina Básica-
dc.subjectCIENCIAS MÉDICAS Y DE LA SALUD-
dc.titleInfluence of a lactobacillus probiotic strain on the intestinal ecosystem in a stress model in mouse-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
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