Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Soria, Elio Andres | - |
| dc.creator | Quiroga, Patricia L. | - |
| dc.creator | Albrecht, Claudia | - |
| dc.creator | Ramos Elizagaray, Sabina I. | - |
| dc.creator | Cantero, Juan J. | - |
| dc.creator | Bongiovanni, Guillermina Azucena | - |
| dc.date | 2017-01-18T19:52:23Z | - |
| dc.date | 2017-01-18T19:52:23Z | - |
| dc.date | 2014-06 | - |
| dc.date | 2017-01-17T19:14:46Z | - |
| dc.date.accessioned | 2019-04-29T15:54:27Z | - |
| dc.date.available | 2019-04-29T15:54:27Z | - |
| dc.identifier | Soria, Elio Andres; Quiroga, Patricia L.; Albrecht, Claudia; Ramos Elizagaray, Sabina I.; Cantero, Juan J.; et al.; Development of an Antioxidant Phytoextract of Lantana grisebachii with Lymphoprotective Activity against In Vitro Arsenic Toxicity; Hindawi Publishing Corporation; Advances in Pharmacological Sciences; 6-2014; 1-7; 416761 | - |
| dc.identifier | 1687-6334 | - |
| dc.identifier | http://hdl.handle.net/11336/11581 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/305159 | - |
| dc.description | Phytochemicals have been presumed to possess prophylactic and curative properties in several pathologies, such as arsenic- (As-induced immunosuppression. Our aim was to discover a lymphoprotective extract from Lantana grisebachii Stuck. (Verbenaceae)(LG). We assessed its bioactivity and chemical composition using cell-based assays. Fractions produced from a hexane extract acutely induced nitrite formation in T- Activated cell cultures (P < 0.0001). Water extraction released a fraction lacking nitrite inducing activity in both lymphocyte types. Aqueous LG was found to be safe in proliferated and proliferating cells. The infusion-derived extract presented better antioxidant capacity in proportion to phenolic amount in lymphocytes (infusive LG- 1i at 100g/mL), which protected them against in vitro As-induced lymphotoxicity (P < 0.0001). This infusive LG phytoextract contained 10.23 ± 0.43mg/g of phenolics, with 58.46% being flavonoids. Among the phenolics, the only predominant compound was 0.723 mg of chlorogenic acid per gram of dry plant, in addition to 10 unknown minor compounds. A fatty acid profile was assessed. It contained one-third of saturated fatty acids, one-third of 9, followed by 6 (∼24%) and 3 (∼4%), and scarce 7. Summing up, L. grisebachiiwas a source of bioactive and lymphoprotective compounds, which could counteract As-toxicity. This supports its phytomedical use and research in order to reduce As-related dysfunctions | - |
| dc.description | Fil: Soria, Elio Andres. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Biologia Celular; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina | - |
| dc.description | Fil: Quiroga, Patricia L.. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Biologia Celular; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina | - |
| dc.description | Fil: Albrecht, Claudia. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Biologia Celular; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina | - |
| dc.description | Fil: Ramos Elizagaray, Sabina I.. Consejo Interuniversitario Nacional; Argentina | - |
| dc.description | Fil: Cantero, Juan J.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto Multidisciplinario de Biología Vegetal (p); Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria; Argentina | - |
| dc.description | Fil: Bongiovanni, Guillermina Azucena. Universidad Nacional del Comahue. Facultad de Ciencis Agrarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Hindawi Publishing Corporation | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/aps/2014/416761/ | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1155/2014/416761 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | LANTANA GRISEBACHII | - |
| dc.subject | LYMPHOPROTECTIVE ACTIVITY | - |
| dc.subject | ARSENIC TOXICITY | - |
| dc.subject | ANTIOXIDANTS | - |
| dc.subject | Farmacología y Farmacia | - |
| dc.subject | Medicina Básica | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Development of an Antioxidant Phytoextract of Lantana grisebachii with Lymphoprotective Activity against In Vitro Arsenic Toxicity | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.