Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Serrano, Mariana Paula | - |
| dc.creator | Lorente, Carolina | - |
| dc.creator | Borsarelli, Claudio Darío | - |
| dc.creator | Thomas, Andrés Héctor | - |
| dc.date | 2016-05-03T16:42:34Z | - |
| dc.date | 2016-05-03T16:42:34Z | - |
| dc.date | 2015-04 | - |
| dc.date | 2016-05-06 15:52:43.262787-03 | - |
| dc.date.accessioned | 2019-04-29T15:53:35Z | - |
| dc.date.available | 2019-04-29T15:53:35Z | - |
| dc.date.issued | 2015-04 | - |
| dc.identifier | Serrano, Mariana Paula; Lorente, Carolina; Borsarelli, Claudio Darío; Thomas, Andrés Héctor; Unraveling the degradation mechanism of purine nucleotides photosensitized by pterins: the role of charge-transfer steps; Royal Society Of Chemistry; Chemphyschem; 16; 10; 4-2015; 2244-2252 | - |
| dc.identifier | 1463-9076 | - |
| dc.identifier | http://hdl.handle.net/11336/5473 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/304814 | - |
| dc.description | Photosensitized reactions contribute to the generation of skin cancer and are used in many applications. The photosensitizers may act through different mechanisms. It is currently accepted that if the photosensitizer generates singlet molecular oxygen (1O2) upon irradiation, the target molecule is able to be oxidized by this ROS and the reaction needs dissolved O2 to take place, the reaction is named a 1O2 -mediated oxidation (type II mechanism). However, this assumption is not always precise. As an example of this type of case, we present here a study on the degradation of 2´-deoxyguanosine 5´-monophosphate (dGMP) photosensitized by pterin. We propose a general mechanism to explain by the degradation of biological targets, such as nucleotides, photosensitized by pterins, naturally occurring 1O2 photosensitizers, takes place through an electron-transfer initiated process (type I mechanism), being almost negligible the contribution of the 1O2 -mediated oxidation. | - |
| dc.description | Fil: Serrano, Mariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de La Plata; Argentina | - |
| dc.description | Fil: Lorente, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de La Plata; Argentina | - |
| dc.description | Fil: Borsarelli, Claudio Darío. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Santiago del Estero; Argentina. Universidad Nacional de Santiago del Estero; Argentina | - |
| dc.description | Fil: Thomas, Andrés Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de La Plata; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Royal Society Of Chemistry | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/wol1/doi/10.1002/cphc.201500219/abstract | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/10.1002/cphc.201500219 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/cphc.201500219 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | PHOTOSENSITIZATION | - |
| dc.subject | PTERIN | - |
| dc.subject | ELECTRON TRANSFER | - |
| dc.subject | TYPE I/TYPE II | - |
| dc.subject | dGMP | - |
| dc.subject | GUANINE RADICAL | - |
| dc.subject | Físico-Química, Ciencia de los Polímeros, Electroquímica | - |
| dc.subject | Ciencias Químicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Unraveling the degradation mechanism of purine nucleotides photosensitized by pterins: the role of charge-transfer steps | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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