Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Barrea, Andres Alberto | - |
| dc.creator | Hernandez, Matias Ezequiel | - |
| dc.creator | Spies, Ruben Daniel | - |
| dc.date | 2018-07-25T17:47:12Z | - |
| dc.date | 2018-07-25T17:47:12Z | - |
| dc.date | 2017-06-15 | - |
| dc.date | 2018-07-04T19:19:58Z | - |
| dc.date.accessioned | 2019-04-29T15:46:13Z | - |
| dc.date.available | 2019-04-29T15:46:13Z | - |
| dc.date.issued | 2017-06-15 | - |
| dc.identifier | Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Spies, Ruben Daniel; Optimal chemotherapy schedules from tumor entropy; Sociedade Brasileira de Matemática Aplicada e Computacional; Matematica Aplicada E Computacional; 36; 2; 15-6-2017; 991-1008 | - |
| dc.identifier | 0101-8205 | - |
| dc.identifier | http://hdl.handle.net/11336/53100 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/301555 | - |
| dc.description | We propose a model for the dynamics of an heterogeneous tumor, which consists of sensitive and resistant cells. The model is analyzed and validated using a cellular automaton whose local rules are classic and widely accepted in Biology. We then extend the model to a tumor under therapy. We consider Shannon’s entropy for the tumor and analyze the problem of minimizing this entropy. From this minimization problem, we find viable therapies that maintain at low level the entropy of the tumor. These therapies could provide a valuable tool for designing protocols for disease control, maintaining a very low growth level, while the tumor remains composed mainly of sensitive cells. | - |
| dc.description | Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina | - |
| dc.description | Fil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina | - |
| dc.description | Fil: Spies, Ruben Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Matemática Aplicada del Litoral. Universidad Nacional del Litoral. Instituto de Matemática Aplicada del Litoral; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Sociedade Brasileira de Matemática Aplicada e Computacional | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s40314-015-0275-7 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs40314-015-0275-7 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.biorxiv.org/content/early/2018/02/10/263327 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.subject | CANCER | - |
| dc.subject | CHEMOTHERAPHY | - |
| dc.subject | ENTROPY | - |
| dc.subject | OPTIMIZATION | - |
| dc.subject | Matemática Pura | - |
| dc.subject | Matemáticas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Optimal chemotherapy schedules from tumor entropy | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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