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| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.creator | Carpentieri, Agata Rita | - |
| dc.creator | Oliva, Clara | - |
| dc.creator | Diez Noguera, Antoni | - |
| dc.creator | Cambras, Trinitat | - |
| dc.date | 2017-01-13T21:17:45Z | - |
| dc.date | 2017-01-13T21:17:45Z | - |
| dc.date | 2015-07 | - |
| dc.date | 2017-01-13T19:42:25Z | - |
| dc.date.accessioned | 2019-04-29T15:42:07Z | - |
| dc.date.available | 2019-04-29T15:42:07Z | - |
| dc.date.issued | 2015-07 | - |
| dc.identifier | Carpentieri, Agata Rita; Oliva, Clara; Diez Noguera, Antoni; Cambras, Trinitat; Melatonin administration modifies circadian motor activity under constant light depending on the lighting conditions during suckling; Taylor & Francis; Chronobiology International; 32; 7; 7-2015; 994-1004 | - |
| dc.identifier | 0742-0528 | - |
| dc.identifier | http://hdl.handle.net/11336/11358 | - |
| dc.identifier | 1525-6073 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/299918 | - |
| dc.description | Early lighting conditions have been described to produce long-term effects on circadian behavior, which may also influence the response to agents acting on the circadian system. It has been suggested that melatonin (MEL) may act on the circadian pacemaker and as a scavenger of reactive oxygen and nitrogen species. Here, we studied the oxidative and behavioral changes caused by prolonged exposure to constant light (LL) in groups of rats that differed in MEL administration and in lighting conditions during suckling. The rats were exposed to either a light–dark cycle (LD) or LL. At 40 days old, rats were treated for 2 weeks with a daily subcutaneous injection of MEL (10 mg/kg body weight) or a vehicle at activity onset. Blood samples were taken before and after treatment, to determine catalase (CAT) activity and nitrite level in plasma. As expected, LL-reared rats showed a more stable motor activity circadian rhythm than LD rats. MEL treatment produced more reactivity in LD- than in LL rats, and was also able to alter the phase of the rhythm in LD rats. There were no significant differences in nitrite levels or CAT activity between the groups, although both variables increased with time. Finally, we also tested depressive signs by means of sucrose consumption, and anhedonia was found in LD males treated with MEL. The results suggest that the lighting conditions in early infancy are important for the long-term functionality of the circadian system, including rhythm manifestation, responses to MEL and mood alterations. | - |
| dc.description | Fil: Carpentieri, Agata Rita. Universidad de Barcelona. Facultad de Farmacia; España. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Universidad Nacional de Córdoba; Argentina | - |
| dc.description | Fil: Oliva, Clara. Universidad de Barcelona. Facultad de Farmacia; España | - |
| dc.description | Fil: Diez Noguera, Antoni. Universidad de Barcelona. Facultad de Farmacia; España | - |
| dc.description | Fil: Cambras, Trinitat. Universidad de Barcelona. Facultad de Farmacia; España | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Taylor & Francis | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://www.tandfonline.com/doi/full/10.3109/07420528.2015.1060243 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/53427 | - |
| dc.subject | MELATONIN | - |
| dc.subject | CIRCADIAN RHYTHMS | - |
| dc.subject | SYNCHRONIZATION | - |
| dc.subject | CONSTANT LIGHT | - |
| dc.subject | Bioquímica y Biología Molecular | - |
| dc.subject | Ciencias Biológicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Melatonin administration modifies circadian motor activity under constant light depending on the lighting conditions during suckling | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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