Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.provenanceCONICET-
dc.creatorVillalta, Jorge Ignacio-
dc.creatorLandi, Sofía Mariana-
dc.creatorFló, Ana-
dc.creatorDella Maggiore, Valeria Monica-
dc.date2017-04-18T15:49:36Z-
dc.date2017-04-18T15:49:36Z-
dc.date2015-06-
dc.date2017-03-30T14:53:14Z-
dc.date.accessioned2019-04-29T15:39:31Z-
dc.date.available2019-04-29T15:39:31Z-
dc.date.issued2015-06-
dc.identifierVillalta, Jorge Ignacio; Landi, Sofía Mariana; Fló, Ana; Della Maggiore, Valeria Monica; Extinction interferes with the retrieval of visuomotor memories through a mechanism involving the sensorimotor cortex; Oxford University Press; Cerebral Cortex; 25; 6; 6-2015; 1535-1543-
dc.identifier1047-3211-
dc.identifierhttp://hdl.handle.net/11336/15358-
dc.identifier1460-2199-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/298768-
dc.descriptionSavings is a fundamental property of learning. In motor adaptation, it refers to the improvement in learning observed when adaptation to a perturbation A (A1) is followed by re-adaptation to the same perturbation (A2). A common procedure to equate the initial level of error across sessions consists of restoring native sensorimotor coordinates by inserting null—unperturbed—trials (N) just before re-adaptation (washout). Here, we hypothesized that the washout is not innocuous but interferes with the expression of the new memory at recall. To assess this possibility, we measured savings following the A1NA2 protocol, where A was a 40° visual rotation. In Experiment 1, we increased the time window between N and A2 from 1 min to 24 h. This manipulation increased the amount of savings during middle to late phases of adaptation, suggesting that N interfered with the retrieval of A. In Experiment 2, we used repetitive TMS to evaluate if this interference was partly mediated by the sensorimotor cortex (SM). We conclude that the washout does not just restore the unperturbed sensorimotor coordinates, but inhibits the expression of the recently acquired visuomotor map through a mechanism involving SM. Our results resemble the phenomenon of extinction in classical conditioning.-
dc.descriptionFil: Villalta, Jorge Ignacio. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Landi, Sofía Mariana. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Fló, Ana. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.descriptionFil: Della Maggiore, Valeria Monica. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherOxford University Press-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/cercor/bht346-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/cercor/article-lookup/doi/10.1093/cercor/bht346-
dc.rightsinfo:eu-repo/semantics/restrictedAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.source.urihttp://hdl.handle.net/11336/15358-
dc.subjectADAPTATION-
dc.subjectANTEROGRADE INTERFERENCE-
dc.subjectMOTOR LEARNING-
dc.subjectNULL TRIALS-
dc.subjectSENSORIMOTOR CORTEX-
dc.subjectTRANSCRANIAL MAGNETIC STIMULATION-
dc.subjectOtras Ciencias Biológicas-
dc.subjectCiencias Biológicas-
dc.subjectCIENCIAS NATURALES Y EXACTAS-
dc.titleExtinction interferes with the retrieval of visuomotor memories through a mechanism involving the sensorimotor cortex-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
Aparece en las colecciones: CONICET

Ficheros en este ítem:
No hay ficheros asociados a este ítem.