Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Pinazo, Maria Jesús | - |
| dc.creator | Thomas Carazo, María del Carmen | - |
| dc.creator | Bua, Jacqueline Elena | - |
| dc.creator | Perrone, Alina Elizabeth | - |
| dc.creator | Schijman, Alejandro Gabriel | - |
| dc.creator | Viotti, Rodolfo Jorge | - |
| dc.creator | Ramsey, Janine | - |
| dc.creator | Ribeiro, Isabela | - |
| dc.creator | Sosa-estani, Sergio Alejandro | - |
| dc.creator | López, Manuel Carlos | - |
| dc.creator | Gascon, Joaquim | - |
| dc.date | 2018-01-15T19:48:23Z | - |
| dc.date | 2018-01-15T19:48:23Z | - |
| dc.date | 2014-03 | - |
| dc.date | 2018-01-11T13:50:44Z | - |
| dc.date.accessioned | 2019-04-29T15:39:04Z | - |
| dc.date.available | 2019-04-29T15:39:04Z | - |
| dc.date.issued | 2014-03 | - |
| dc.identifier | Viotti, Rodolfo Jorge; Thomas Carazo, María del Carmen; Gascon, Joaquim; Pinazo, Maria Jesús; López, Manuel Carlos; Bua, Jacqueline Elena; et al.; Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review; Taylor & Francis; Expert Review of Anti-infective Therapy; 12; 4; 3-2014; 479-496 | - |
| dc.identifier | 1478-7210 | - |
| dc.identifier | http://hdl.handle.net/11336/33330 | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/298560 | - |
| dc.description | The most neglected aspects of Chagas disease (CD) have been patient care and treatment. Despite recent progress in the development of potentially improved drugs, there is no consensus among different research groups on the lack of therapeutic response markers to evaluate efficacy of newly proposed drugs early after treatment. A systematic review of current evidence regarding molecules which are potential biomarkers for therapeutic response has been conducted using quality assessment and target responses as primary criteria. The review provides a panorama of the cumulative evidence and specific needs for development of a battery of complementary biomarkers which together fulfill ideal or acceptable criteria to evaluate early responses to treatment for chronic CD. There are several marker candidates which together may fulfill acceptable criteria to indicate the efficacy of a trypanocidal treatment. Data from ongoing studies are considered essential to improve assessment of existing markers and to identify those for early follow-up of treated patients. | - |
| dc.description | Fil: Pinazo, Maria Jesús. Universidad de Barcelona; España | - |
| dc.description | Fil: Thomas Carazo, María del Carmen. Consejo Superior de Investigaciones Científicas; España | - |
| dc.description | Fil: Bua, Jacqueline Elena. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Perrone, Alina Elizabeth. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: Schijman, Alejandro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina | - |
| dc.description | Fil: Viotti, Rodolfo Jorge. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; Argentina | - |
| dc.description | Fil: Ramsey, Janine. Instituto Nacional de Salud Pública. Centro Regional de Investigación en Salud Pública; México | - |
| dc.description | Fil: Ribeiro, Isabela. Drugs for Neglected Diseases Initiative; Suiza | - |
| dc.description | Fil: Sosa-estani, Sergio Alejandro. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | - |
| dc.description | Fil: López, Manuel Carlos. Consejo Superior de Investigaciones Científicas; España | - |
| dc.description | Fil: Gascon, Joaquim. Universidad de Barcelona; España | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Taylor & Francis | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1586/14787210.2014.899150 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1586/14787210.2014.899150 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/33330 | - |
| dc.subject | Biological marker | - |
| dc.subject | Biomarker | - |
| dc.subject | Chagas disease | - |
| dc.subject | Cure marker | - |
| dc.subject | Humoral and cellular immune response | - |
| dc.subject | PCR | - |
| dc.subject | Treatment | - |
| dc.subject | Trypanosoma cruzi | - |
| dc.subject | Salud Ocupacional | - |
| dc.subject | Ciencias de la Salud | - |
| dc.subject | CIENCIAS MÉDICAS Y DE LA SALUD | - |
| dc.title | Biological markers for evaluating therapeutic efficacy in Chagas disease, a systematic review | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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