Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Crespo Andrada, Karina Fernanda | - |
| dc.creator | Baronetti, Jose Luis | - |
| dc.creator | Quinteros, Melisa de los Ángeles | - |
| dc.creator | Páez, Paulina Laura | - |
| dc.creator | Paraje, María Gabriela | - |
| dc.date | 2017-09-14T18:18:57Z | - |
| dc.date | 2017-09-14T18:18:57Z | - |
| dc.date | 2016-12 | - |
| dc.date | 2017-09-01T18:05:12Z | - |
| dc.date.accessioned | 2019-04-29T15:34:11Z | - |
| dc.date.available | 2019-04-29T15:34:11Z | - |
| dc.date.issued | 2016-12 | - |
| dc.identifier | Crespo Andrada, Karina Fernanda; Baronetti, Jose Luis; Quinteros, Melisa de los Ángeles; Páez, Paulina Laura; Paraje, María Gabriela; Intra- and extracellular biosynthesis and characterization of iron nanoparticles from Prokaryotic microorganisms with anticoagulant activity; Springer; Pharmaceutical Research; 34; 3; 12-2016; 591-598 | - |
| dc.identifier | 0724-8741 | - |
| dc.identifier | http://hdl.handle.net/11336/24263 | - |
| dc.identifier | 1573-904X | - |
| dc.identifier | CONICET Digital | - |
| dc.identifier | CONICET | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/296779 | - |
| dc.description | Background: The use of microorganisms for the synthesis of nanoparticles (NPs) is relatively new in basic research and technology areas. Purpose: This work was conducted to optimized the biosynthesis of iron NPs intra- and extracellular by Escherichia coli or Pseudomonas aeruginosa and to evaluate their anticoagulant activity. Study Design/Methods: The structures and properties of the iron NPs were investigated by Ultraviolet–visible (UV-vis) spectroscopy, Zeta potential, Dynamic light scattering (DLS), Field emission scanning electron microscope (FESEM)/ Energy dispersive X-ray (EDX) and transmission electron microscopy (TEM). Anticoagulant activity was determined by conducting trials of Thrombin Time (TT), Activated Partial Prothrombin Time (APTT) and Prothrombin Time (PT). Results: UV-vis spectrum of the aqueous medium containing iron NPs showed a peak at 275 nm. The forming of iron NPs was confirmed by FESEM/ EDX, and TEM. The morphology was spherical shapes mostly with low polydispersity and the average particle diameter was 23 ± 1 nm. Iron NPs showed anticoagulant activity by the activation of extrinsic pathway. Conclusion: The eco-friendly process of biosynthesis of iron NPs employing prokaryotic microorganisms presents a good anticoagulant activity. This could be explored as promising candidates for a variety of biomedical and pharmaceutical applications. | - |
| dc.description | Fil: Crespo Andrada, Karina Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina | - |
| dc.description | Fil: Baronetti, Jose Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina | - |
| dc.description | Fil: Quinteros, Melisa de los Ángeles. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina | - |
| dc.description | Fil: Páez, Paulina Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Unidad de Investigación y Desarrollo en Tecnología Farmacéutica; Argentina | - |
| dc.description | Fil: Paraje, María Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Springer | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s11095-016-2084-0 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/ 10.1007/s11095-016-2084-0 | - |
| dc.rights | info:eu-repo/semantics/restrictedAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/24263 | - |
| dc.subject | ANTICOAGULANT ACTIVITY | - |
| dc.subject | ESCHERICHIA COLI | - |
| dc.subject | PSEUDOMONAS AERUGINOSA | - |
| dc.subject | MICROBIAL | - |
| dc.subject | Nano-materiales | - |
| dc.subject | Nanotecnología | - |
| dc.subject | INGENIERÍAS Y TECNOLOGÍAS | - |
| dc.title | Intra- and extracellular biosynthesis and characterization of iron nanoparticles from Prokaryotic microorganisms with anticoagulant activity | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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