Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.creatorGaddi, E.-
dc.creatorLaucella, Susana Adriana-
dc.creatorBalbaryski, J.-
dc.creatorCantisano, C.-
dc.creatorBarboni, G.-
dc.creatorCandi, M.-
dc.creatorGiraudi, V.-
dc.date2019-03-14T18:12:18Z-
dc.date2019-03-14T18:12:18Z-
dc.date2008-07-
dc.date2019-03-14T14:15:44Z-
dc.date.accessioned2019-04-29T15:30:57Z-
dc.date.available2019-04-29T15:30:57Z-
dc.date.issued2008-07-
dc.identifierGaddi, E.; Laucella, Susana Adriana; Balbaryski, J.; Cantisano, C.; Barboni, G.; et al.; Prognostic Value of Soluble Intercellular Adhesion Molecule-1 (s-ICAM-1) in HIV-Infected Children; Wiley Blackwell Publishing, Inc; Scandinavian Journal Of Immunology; 52; 6; 7-2008; 628-633-
dc.identifier0300-9475-
dc.identifierhttp://hdl.handle.net/11336/71655-
dc.identifierCONICET Digital-
dc.identifierCONICET-
dc.identifier.urihttp://rodna.bn.gov.ar:8080/jspui/handle/bnmm/295541-
dc.descriptionCentral events in the host defence system and immune-mediated damage are tightly regulated by celladhesion molecules. Sera from 28 human immunodeficiency virus (HIV)-1 infected children divided intogroups according to disease severity, six seroreverting (SR) children and 25 healthy controls were studied todetect the presence of soluble intercellular adhesion molecu le-1 (s-ICAM-1). Soluble ICAM-1 levels werefound to be significantly increased in HIV-infected children in comparison with SR children or healthycontrols. Levels of soluble ICAM-1 were higher in patients with severe forms of HIV-infection than in thosewith a milder form of the disease. Significant differences in titers of s-ICAM-1 were recorded between SRchildren and HIV-infected children with mild disease or healthy controls. There was a significant correlationbetween s-ICAM-1 levels and the concentrations of beta 2 microglobulin (b2m) and, to a lesser extend,immunoglobulin A levels (IgA). Soluble ICAM-1 levels didn't change considerably in HIV-infected childrenin stable clini cal conditions, independently of their clinical stage of the disease, during a follow-up period of9±12 months. Conversely, s-ICAM-1 levels increased simultaneously with the appearance of new well-defined clini cal disorders or decreased during the improvement of clinical conditions. A significant negativecorrelation was recorded between the titers of the s-ICAM-1 and the CD41T-cell levels. These resultssuggest that the s-ICAM-1 might be another useful tool to evaluate disease progression.-
dc.descriptionFil: Gaddi, E.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.descriptionFil: Laucella, Susana Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”. Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben”; Argentina-
dc.descriptionFil: Balbaryski, J.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.descriptionFil: Cantisano, C.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.descriptionFil: Barboni, G.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.descriptionFil: Candi, M.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.descriptionFil: Giraudi, V.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños Pedro Elizalde (ex Casa Cuna); Argentina-
dc.formatapplication/pdf-
dc.formatapplication/pdf-
dc.languageeng-
dc.publisherWiley Blackwell Publishing, Inc-
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1111/j.1365-3083.2000.00820.x-
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/j.1365-3083.2000.00820.x-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/-
dc.sourcereponame:CONICET Digital (CONICET)-
dc.sourceinstname:Consejo Nacional de Investigaciones Científicas y Técnicas-
dc.sourceinstacron:CONICET-
dc.subjectHIV-
dc.subjectCHILDREN-
dc.subjectMedicina Critica y de Emergencia-
dc.subjectMedicina Clínica-
dc.subjectCIENCIAS MÉDICAS Y DE LA SALUD-
dc.titlePrognostic Value of Soluble Intercellular Adhesion Molecule-1 (s-ICAM-1) in HIV-Infected Children-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:eu-repo/semantics/publishedVersion-
dc.typeinfo:ar-repo/semantics/articulo-
Aparece en las colecciones: CONICET

Ficheros en este ítem:
No hay ficheros asociados a este ítem.