Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.provenance | CONICET | - |
| dc.creator | Otarola, Jessica Johana | - |
| dc.creator | Lista, Adriana Guillermina | - |
| dc.creator | Fernández Band, Beatriz Susana | - |
| dc.creator | Garrido, Mariano Enrique | - |
| dc.date | 2016-03-09T18:31:33Z | - |
| dc.date | 2016-03-09T18:31:33Z | - |
| dc.date | 2015-01 | - |
| dc.date | 2016-03-30 10:35:44.97925-03 | - |
| dc.date.accessioned | 2019-04-29T15:30:03Z | - |
| dc.date.available | 2019-04-29T15:30:03Z | - |
| dc.date.issued | 2016-03-09T18:31:33Z | - |
| dc.date.issued | 2016-03-09T18:31:33Z | - |
| dc.date.issued | 2015-01 | - |
| dc.date.issued | 2016-03-30 10:35:44.97925-03 | - |
| dc.identifier | Otarola, Jessica Johana; Lista, Adriana Guillermina; Fernández Band, Beatriz Susana; Garrido, Mariano Enrique; Capillary electrophoresis to determine entrapment efficiency of a nanostructured lipid carrier loaded with piroxicam; Elsevier; Journal of Pharmaceutical Analysis; 5; 1; 1-2015; 70-73 | - |
| dc.identifier | 2095-1779 | - |
| dc.identifier | http://hdl.handle.net/11336/4710 | - |
| dc.identifier.uri | http://rodna.bn.gov.ar:8080/jspui/handle/bnmm/295261 | - |
| dc.description | A simple and fast capillary electrophoresis method has been developed to determine the amount of piroxicam loaded in a drug delivery system based on nanostructured lipid carriers (NLC). The entrapment efficiency of the nanostructured lipid carrier was estimated by measuring the concentration of drug not entrapped in a suspension of NLC. The influence of different parameters on migration times, peak symmetry, efficiency and resolution was studied; these parameters included the pH of the electrophoretic buffer solution and the applied voltage. The piroxicam peak was obtained with a satisfactory resolution. The separation was carried out using a running buffer, which it is composed of 50 mmol L-1 ammonium acetate and 13.75 mmol L-1 ammonia at pH 9. The optimal voltage was 20kV and the cartridge temperature was 20°C. The corresponding calibration curve was linear over the range of 2.7 ? 5.4 µg mL-1 of NLC suspension. The reproducibility of migration time and peak area were investigated, and the obtained RSD% values (n = 5) were 0.99 and 2.13, respectively. | - |
| dc.description | Fil: Otarola, Jessica Johana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Lista, Adriana Guillermina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Fernández Band, Beatriz Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina | - |
| dc.description | Fil: Garrido, Mariano Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Instituto de Química del Sur; Argentina | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.format | application/pdf | - |
| dc.language | eng | - |
| dc.publisher | Elsevier | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jpha.2014.05.003 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S2095177914000446 | - |
| dc.relation | info:eu-repo/semantics/altIdentifier/issn/2095-1779 | - |
| dc.rights | info:eu-repo/semantics/openAccess | - |
| dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ | - |
| dc.source | reponame:CONICET Digital (CONICET) | - |
| dc.source | instname:Consejo Nacional de Investigaciones Científicas y Técnicas | - |
| dc.source | instacron:CONICET | - |
| dc.source.uri | http://hdl.handle.net/11336/4710 | - |
| dc.subject | CAPILLARY ELECTROPHORESIS | - |
| dc.subject | DRUG DELIVERY SYSTEM | - |
| dc.subject | NANOSTRUCTURED LIPID CARRIER | - |
| dc.subject | PIROXICAM | - |
| dc.subject | Química Analítica | - |
| dc.subject | Ciencias Químicas | - |
| dc.subject | CIENCIAS NATURALES Y EXACTAS | - |
| dc.title | Capillary electrophoresis to determine entrapment efficiency of a nanostructured lipid carrier loaded with piroxicam | - |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:ar-repo/semantics/articulo | - |
| Aparece en las colecciones: | CONICET | |
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